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Case Reports
. 2021 May 24;9(5):e04248.
doi: 10.1002/ccr3.4248. eCollection 2021 May.

Successful treatment of pulmonary aspergillosis due to Aspergillus fumigatus in a child affected by systemic lupus erythematosus: A case report from Northeastern Iran

Affiliations
Case Reports

Successful treatment of pulmonary aspergillosis due to Aspergillus fumigatus in a child affected by systemic lupus erythematosus: A case report from Northeastern Iran

Elham Kashefi et al. Clin Case Rep. .

Abstract

A6-year-old girl affected to systemic lupus erythematosus with symptoms of fever, weakness, and lethargy, cough, chest pain, and abnormalchest x-ray. The isolated Aspergillus fumigatus was identified using partial calmodulin gene sequencing. Gradual improvement was observed onday 19 of treatment with amphotericinB (50 mg /day).

Keywords: Aspergillusfumigatus; Iran; child; systemic lupus erythematosus.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Chest X‐ray revealed consolidation in the left lung, arrow A and B, and it manifested collapse, in the left lung, arrow C
FIGURE 2
FIGURE 2
Appearance of Aspergillus fumigatus colonies on sabouraud dextrose agar with chloramphenicol (SC)
FIGURE 3
FIGURE 3
Chest X‐ray revealed gradual recovery in the lung left, after chest tube and treatment with amphotericin B

References

    1. Bernatsky S, Boivin JF, Joseph L, et al. Mortality in systemic lupus erythematosus. Arthritis Rheum. 2006;54(8):2550‐2557. - PubMed
    1. Chai LY‐A, Hsu L‐Y. Recent advances in invasive pulmonary aspergillosis. Curr Opin Pulmonary Med. 2011;17(3):160‐166. - PubMed
    1. Canova E, Rosa D, Vallada M, Silva C. Invasive aspergillosis in juvenile systemic lupus erythematosus. A clinicopathologic case. Clin Exp Rheumatol. 2002;20(5):736. - PubMed
    1. Zarrinfar H, Mirhendi H, Makimura K, Satoh K, Khodadadi H, Paknejad O. Use of mycological, nested PCR, and real‐time PCR methods on BAL fluids for detection of Aspergillus fumigatus and A. flavus in solid organ transplant recipients. Mycopathologia. 2013;176(5–6):377‐385. - PubMed
    1. Zanganeh E, Zarrinfar H, Rezaeetalab F, et al. Predominance of non‐fumigatus Aspergillus species among patients suspected to pulmonary aspergillosis in a tropical and subtropical region of the Middle East. Microb Pathog. 2018;116:296‐300. - PubMed

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