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. 2021 May 26;8(5):201585.
doi: 10.1098/rsos.201585.

Adsorption and release on three-dimensional graphene oxide network structures

Sunnam Kim  1 , Sho Moriya  1 , Sakura Maruki  1 , Tuyoshi Fukaminato  1 , Tomonari Ogata  1 , Seiji Kurihara  1
Affiliations

Adsorption and release on three-dimensional graphene oxide network structures

Sunnam Kim et al. R Soc Open Sci. .

Abstract

In this study, three-dimensional network architectures are constructed using nano-sized graphene oxide (nGO) as the building block. The cross-linking reaction of nGO is conducted in sub-micrometre water droplets in an emulsion system to control the size of the networks by restricting the reaction space. Two types of three-dimensional GO networks with different cross-linking lengths were constructed, and their methyl orange adsorption and release behaviours were investigated under external stimuli, such as thermal treatment, ultrasonic wave treatment and near-infrared light irradiation.

Keywords: drug delivery; graphene oxide; network structure.

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Figures

Figure 1.
Figure 1.
HR-TEM images of PGNF (a,b) and nGO (c,d).
Figure 2.
Figure 2.
FTIR of nGO, nGO-EDA and nGO-OBEA.
Figure 3.
Figure 3.
Synthetic schemes of nGO-EDA and nGO-OBEA (a). DLS measurement of water droplets of w/o emulsion (b), where solid line is for number and broken line is for intensity. Calculation results of the cross-link lengths for nGO-EDA (i) and nGO-OBEA (ii) by Spartan ′14 (c). The nGO structure is simplified and represented by one benzene group.
Figure 4.
Figure 4.
SEM and TEM images of nGO-EDA (a,b) and nGO-OBEA (c,d), scale bar is 500 nm; AFM images of nGO-EDA (e) and nGO-OBEA (f).
Figure 5.
Figure 5.
Absorption spectra of methyl orange solution before and after the addition of nGO, nGO-EDA and nGO-OBEA. Molecular structure of methyl orange.
Figure 6.
Figure 6.
Release rate of methyl orange adsorbed on the nGO-EDA (a), and nGO-OBEA (b) under external stimuli, such as heating at 50°C (○), heating at 80°C (Δ), ultrasonic treatment (□), NIR irradiation (▪) and storing in the dark without stimuli(x).
See this image and copyright information in PMC

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