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. 2021 Sep;91(9):1744-1750.
doi: 10.1111/ans.16936. Epub 2021 Jun 3.

Experience with NovoSorb® Biodegradable Temporising Matrix in reconstruction of complex wounds

Henry Li  1 , Pelicia Lim  1   2 , Edward Stanley  1 , Geoffrey Lee  1   2 , Sandra Lin  1 , Derek Neoh  1   2 , Julian Liew  1   3 , Sally Kiu-Huen Ng  1   2   4
Affiliations

Experience with NovoSorb® Biodegradable Temporising Matrix in reconstruction of complex wounds

Henry Li et al. ANZ J Surg. 2021 Sep.

Abstract

Background: The NovoSorb® Biodegradable Temporising Matrix (BTM) is a synthetic polyurethane dermal matrix used to reconstruct complex wounds including deep dermal and full-thickness burns, necrotising fasciitis and free flap donor site. We hope to further explore its potential applications in this series.

Methods: Patients who received BTM application across four centres over an 18-month period were included. Patients were followed up to assess BTM and graft take, the aesthetic, the return of sensation and complications.

Results: A total of 27 patients with 35 wounds were identified with a range of aetiologies. Thirty-three wounds had 100% integration of BTM at the time of sealing membrane removal. Seven wounds had partial graft loss that later healed by secondary intention. In two cases, re-epithelialisation occurred with BTM alone without split-skin graft.

Conclusion: BTM offers a safe and reliable reconstructive option in challenging wounds that would otherwise require more complex operations.

Keywords: Biodegradable Temporising Matrix; synthetic dermal matrix; wound reconstruction.

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Conflict of interest statement

There are no conflicts of interest to disclose except that author Julian Liew holds minor shares in the PolyNovo.

Figures

Fig 1
Fig 1
Right calcaneal pressure sore with osteomyelitis reconstructed—(a) with Biodegradable Temporising Matrix after delamination. (b) Result at 18 months post‐operatively.
Fig 2
Fig 2
Left knee wound dehiscence with underlying metalware. (a) Reconstructed with Biodegradable Temporising Matrix (BTM) over scarred patella tendon (b) at 12 months post‐reconstruction, (c) second reconstruction with a local perforator flap and BTM to the donor site and (d) at 6 months post‐reconstruction.
Fig 3
Fig 3
(a) Failed full‐thickness skin graft on the dorsum of the nose with a separate foci of basal cell carcinoma (BCC) on the left nasal alar. (b) Debridement and excision of left nasal alar BCC en bloc and resurface with Biodegradable Temporising Matrix (c) at 6 months follow‐up.
See this image and copyright information in PMC

References

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