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Randomized Controlled Trial
. 2021 Mar;18(1):44-60.
doi: 10.1007/s10393-021-01524-0. Epub 2021 Jun 4.

Hesitancy Toward a COVID-19 Vaccine

Affiliations
Randomized Controlled Trial

Hesitancy Toward a COVID-19 Vaccine

Linda Thunström et al. Ecohealth. 2021 Mar.

Abstract

The scientific community has come together in a mass mobilization to combat the public health risks of COVID-19, including efforts to develop a vaccine. However, the success of any vaccine depends on the share of the population that gets vaccinated. We designed a survey experiment in which a nationally representative sample of 3,133 adults in the USA stated their intentions to vaccinate themselves and their children for COVID-19. The factors that we varied across treatments were: the stated severity and infectiousness of COVID-19 and the stated source of the risk information (White House or the Centers for Disease Control). We find that 20% of people in the USA intend to decline the vaccine. We find no statistically significant effect on vaccine intentions from the severity of COVID-19. In contrast, we find that the degree of infectiousness of the coronavirus influences vaccine intentions and that inconsistent risk messages from public health experts and elected officials may reduce vaccine uptake. However, the most important determinants of COVID-19 vaccine hesitancy seem to be distrust of the vaccine safety (including uncertainty due to vaccine novelty), as well as general vaccine avoidance, as implied by not having had a flu shot in the last two years.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Density distributions of perceived probability of infection across treatments
Fig. 2
Fig. 2
Mean perceived risk of infection and vaccine uptake across treatments
Fig. 3
Fig. 3
The effects of treatments on perceived risk—marginal effects from a zero–one inflated beta regression
Fig. 4
Fig. 4
Determinants of decision to vaccinate for COVID-19—average marginal effects from a probit regression
Fig. 5
Fig. 5
Reasons for declining the COVID-19 vaccine
Fig. 6
Fig. 6
Potential proportions of the population immunized

References

    1. ABC news/Ipsos poll (2020), Topline and Methodology, https://www.scribd.com/document/460461528/ABC-News-Ipsos-Poll-May-7-2020, Retrieved June 22 2020.
    1. Aguas, R., Corder, R. M., King, J. G., Goncalves, G., Ferreira, M. U., and Gomes, M. G. M. (2020). Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics. medRxiv.
    1. Alberini A, Ščasný M. Exploring heterogeneity in the value of a statistical life: Cause of death v. risk perceptions. Ecological Economics. 2013;94:143–155. doi: 10.1016/j.ecolecon.2013.07.012. - DOI
    1. ASTHO. Communicating Effectively About Vaccines: Summary of a Survey of U.S. Parents and Guardians. Arlington, VA: Association of State and Territorial Health Officials, 2010.
    1. Athey S, Imbens GW. The econometrics of randomized experiments. In: Banerjee AV, Duflo E, editors. Handbook of Economic Field Experiments. Amsterdam, Netherlands: North-Holland; 2017. pp. 73–140.

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