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Review
. 2021 Jun 4;22(8):38.
doi: 10.1007/s11934-021-01057-7.

Improving Compliance with 24-H Urine Collections: Understanding Inadequacies in the Collection Process and Risk Factors for Poor Compliance

Affiliations
Review

Improving Compliance with 24-H Urine Collections: Understanding Inadequacies in the Collection Process and Risk Factors for Poor Compliance

Alice Xiang et al. Curr Urol Rep. .

Abstract

Purpose of review: The purpose of this review paper is to describe the 24-h urine collection in terms of its utility, collection process, and common problems with its acquisition.

Recent findings: Although 24-h urine collections are standard of care for high-risk stone formers, several nuances in test acquisition including inaccurate urine collections 50% of the time and poor patient compliance limit its potential utility. Compliance in obtaining 24-h urine collections has been shown to be improved in patients who have not undergone surgical treatment of urinary calculi, patients with metabolic stone disease or family history of stone disease, Caucasian ethnicity, and in those with more sedentary occupations. Studies show conflicting data of compliance regarding patient age and gender. Physicians must understand the difficulties regarding 24-h urine collections including patient compliance, variability between collections, and complexities with interpretation to best utilize this tool in guiding clinical management for the treatment of nephrolithiasis.

Keywords: 24-h urine; Nephrolithiasis; Poor compliance; Urine analysis; Urine collection process.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
    1. •• Pearle MS, Goldfarb DS, Assimos DG, Curhan G, Denu-Ciocca CJ, Matlaga BR, et al. Medical management of kidney stones: AUA guideline. J Urol. 2014;192(2):325–6. https://doi.org/10.1016/j.juro.2014.05.006 AUA core curriculum and guidelines are based on the information initially published in this paper describing medical management of renal stones. - DOI
    1. •• Leslie SW, Sajjad H, Bashir K. 24-hour urine testing for nephrolithiasis interpretation. [Updated 2020 Oct 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482448/ . Recent educational update article on 24-h urine utility and details of collection process.
    1. Sohgaura A, Bigoniya P. A Review on epidemiology and etiology of renal stone. Am J Drug Discov Dev. 2017;7:54–62. https://doi.org/10.3923/ajdd.2017.54.62 . - DOI
    1. Ennis JL, Asplin JR. The role of the 24-h urine collection in the management of nephrolithiasis. Int J Surg. Dec 2016;36(D):633–7. https://doi.org/10.1016/j.ijsu.2016.11.020 . - DOI - PubMed
    1. Pearle MS, Goldfarb DS, Assimos DG, Curhan G, Denu-Ciocca CJ, Matlaga BR, et al. Medical management of kidney stones: AUA guideline. J Urol. 2014;192(2):316–24. https://doi.org/10.1016/j.juro.2014.05.006 . - DOI - PubMed

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