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. 2022 Mar 9;74(5):909-912.
doi: 10.1093/cid/ciab507.

Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Emil Lesho  1 , Brendan Corey  2 , Francois Lebreton  2 , Ana C Ong  2 , Brett E Swierczewski  2 , Jason W Bennett  2 , Edward E Walsh  1   3 , Patrick McGann  2
Affiliations

Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Emil Lesho et al. Clin Infect Dis. .

Abstract

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.

Keywords: E484K mutation; SARS-CoV-2; lineage B.1.1.345.

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