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Comment
. 2021 Jun 3;28(6):989-990.
doi: 10.1016/j.stem.2021.05.005.

Sweet Dre-ams about intersectional genetics

John P Woods  1 , R Sathish Srinivasan  1 , Lorin E Olson  2
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Sweet Dre-ams about intersectional genetics

John P Woods et al. Cell Stem Cell. .
Free article

Abstract

Specific cell targeting with one site-specific recombinase is challenging. In this issue of Cell Stem Cell, Han et al. (2021) released a collection of Dre drivers and demonstrate how two recombinases can be combined to improve the cell specificity of lineage tracing and gene inactivation in mice.

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