Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep 1:284:117372.
doi: 10.1016/j.envpol.2021.117372. Epub 2021 May 21.

US EPA: Is there room to open a new window for evaluating potential sub-threshold effects and ecological risks?

Evgenios Agathokleous  1 , Damià Barceló  2 , Edward J Calabrese  3
Affiliations

US EPA: Is there room to open a new window for evaluating potential sub-threshold effects and ecological risks?

Evgenios Agathokleous et al. Environ Pollut. .

Abstract

With a rule published on 6 January 2021, the US Environmental Protection Agency (EPA) considers for the first time sub-threshold responses, abandoning the use of default dose-response models. This may affect worldwide scientific research, in terms of research design and methodology, and regulatory actions in China and other countries.

Keywords: Dose-response relationship; Ecological health; Environmental pollution; Hormesis; Pivotal regulatory science; Risk assessment.

PubMed Disclaimer

LinkOut - more resources