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. 2021 Sep;68(9):e29135.
doi: 10.1002/pbc.29135. Epub 2021 Jun 5.

A scoping review of transition interventions for young adults with sickle cell disease

Adrienne Viola  1 , Jerlym Porter  2 , Jelaina Shipman  3 , Ellen Brooks  2 , Cecilia Valrie  3
Affiliations

A scoping review of transition interventions for young adults with sickle cell disease

Adrienne Viola et al. Pediatr Blood Cancer. 2021 Sep.

Erratum in

  • Corrigendum.
    [No authors listed] [No authors listed] Pediatr Blood Cancer. 2022 Jan;69(1):e29414. doi: 10.1002/pbc.29414. Epub 2021 Oct 21. Pediatr Blood Cancer. 2022. PMID: 34842349 No abstract available.

Abstract

Standardized programming for individuals with sickle cell disease (SCD) transitioning from pediatric to adult-centered care does not currently exist, resulting in high rates of mortality and morbidity. This scoping review examines and evaluates the current literature on SCD transition programs and interventions. Eligible studies described an existing program for individuals with SCD aged 12-29 years preparing to transition. The Evidence Project risk-of-bias tool was used to assess article quality. We identified 30 eligible articles, of which, only two were randomized controlled trials. Many studies have incomplete reports of feasibility information, such as completion rates, patient characteristics, and attrition; all studies were limited to a single institution; and most studies were rated high for risk of bias. Progress has been made in designing and gathering initial evaluation data for SCD transition programs; however, there is a need for higher quality studies, consistent assessment, and better dissemination of programs.

Keywords: scoping review; sickle cell disease; transition; young adults.

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Figure 1:
Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) flow diagram
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