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Review
. 2021 Jun 5;20(1):117.
doi: 10.1186/s12933-021-01309-3.

Effect of renal denervation on long-term outcomes in patients with resistant hypertension

Bo Liang  1 , Yi Liang  2 , Rui Li  1 , Ning Gu  3
Affiliations
Review

Effect of renal denervation on long-term outcomes in patients with resistant hypertension

Bo Liang et al. Cardiovasc Diabetol. .

Abstract

Increasing studies strongly prove that renal denervation, a minimally invasive surgery, is a promising new non-drug treatment method that can effectively control blood pressure in patients with resistant hypertension, but the evaluation of the long-term blood pressure control effect of renal denervation for resistant hypertension is still lacking. Here, we critically review current long-term follow-up data about the use of renal denervation for RH to comprehensively evaluate the effectiveness of renal denervation for RH, and to provide practical guidance for practitioners who are establishing a renal denervation service. Limited by the current research, many problems need to be solved before renal denervation is applied to RH. In addition, ambulatory blood pressure should be the first choice for the evaluation of blood pressure. Finally, the continuous antihypertensive effect of renal denervation in different renal denervation systems also needs to be strictly compared.

Keywords: Hypertension; Intervention; Renal denervation; Resistant hypertension.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Effect of renal denervation on long-term outcomes in patients with resistant hypertension. A–C Baseline blood pressure at 12-, 24-, and 36-month. D–F Antihypertensive effect of RDN on blood pressure at 12-, 24-, and 36-month
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