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. 2021 Aug:44:101996.
doi: 10.1016/j.redox.2021.101996. Epub 2021 May 8.

Nutritional cognitive neuroscience of aging: Focus on carotenoids and cognitive frailty

M Cristina Polidori  1 , Wilhelm Stahl  2 , Helen R Griffiths  3
Affiliations

Nutritional cognitive neuroscience of aging: Focus on carotenoids and cognitive frailty

M Cristina Polidori et al. Redox Biol. 2021 Aug.

Abstract

The term "nutritional cognitive neuroscience" was recently established to define a research field focusing on the impact of nutrition on cognition and brain health across the life span. In this overview, we summarize the robust evidence on the role of carotenoids as micronutrients with different biological properties in persons with cognitive (pre)frailty. As neurodegenerative processes during aging occur in a continuum from brain aging to dementia, we propose the name "nutritional cognitive neuroscience of aging" to define research on the role of nutrition and micronutrients in cognitive frailty. Further studies are warranted which integrate carotenoid interventions in multidomain, personalized lifestyle strategies.

Keywords: Alzheimer's disease; Carotenoids; Cognitive frailty; Dementia; Frailty; Micronutrients.

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Conflict of interest statement

No conflict of interest.

Figures

Fig. 1
Fig. 1
Chemical structures of selected carotenoids and retinoids.
See this image and copyright information in PMC

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