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. 2021 Aug:140:53-59.
doi: 10.1016/j.jpsychires.2021.05.031. Epub 2021 May 31.

Impact of peritraumatic dissociation in hospitalized patients with COVID-19 pneumonia: A longitudinal study

Lamyae Benzakour  1 , Olivia Braillard  2 , Viridiana Mazzola  3 , Dominique Gex  4 , Mayssam Nehme  2 , Sigiryia Aebischer Perone  5 , Thomas Agoritsas  6 , Garance Kopp  7 , Cereghetti Sara  8 , Guido Bondolfi  3 , Frederic Lador  9
Affiliations

Impact of peritraumatic dissociation in hospitalized patients with COVID-19 pneumonia: A longitudinal study

Lamyae Benzakour et al. J Psychiatr Res. 2021 Aug.

Abstract

Objective: Psychiatric impact of COVID-19 is still explored and previous data suggest potential risks of anxiety, depression and PTSD related to COVID-19. We aimed to explore the predictive value of risk factors during hospitalization (T0) for COVID-19 for anxiety, depression and PTSD and at three months (T1) because they could differ over these two time points.

Methods: We performed a screening of mental suffering in hospitalized patients for COVID-19, as well as specialized care and three months longitudinal follow-up. We evaluated at T0 and at T1 the prevalence of anxiety, depression and PTSD in survivors who benefited from early detection and treatment, and assessed possible risk factors in adults surviving COVID-19 between the 30th March and the 1st of July 2020.

Results: 109 patients were screened at T0 and 61 of these were reassessed at T1. At T0, we found 44.9% pathological score on peritraumatic dissociation experiences questionnaire (PDEQ), 85.4% of post-traumatic stress disorder symptoms (PTSS), 14.6% of pathological rate of post-traumatic stress disorder scale 5 (PCL5) and at T1, 86.9% of PTSS, 10.6% of pathological rate of PCL5. Finally, PDEQ score at T0 during hospitalization was positively correlated to PCL-5 score at T1 (β = 0.26, p = 0.01) and that was confirmed in multivariate analysis (β = 0.04, p = 0.02 for the log of PCL-5 per point on the PDEQ).

Conclusion: Screening of psychiatric symptoms during hospitalization for COVID-19 should be systematic, especially peritraumatic dissociation to offer an early treatment and prevent PTSD, which seemed frequent for hospitalized patients for COVID-19 at three months.

Keywords: Coronavirus infections; Pneumonia; Post traumatic; Risk factors; Stress disorders.

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