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Review
. 2021 May 15;11(5):1828-1844.
eCollection 2021.

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents

Chella Perumal Palanisamy  1 , Bo Cui  1 , Hongxia Zhang  1 , Mani Panagal  2 , Sivagurunathan Paramasivam  3 , Uma Chinnaiyan  3 , Selvaraj Jeyaraman  4 , Karthigeyan Murugesan  5 , Mauricio Rostagno  6 , Vijayakumar Sekar  7 , Srinivasa Prabhu Natarajan  8
Affiliations
Review

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents

Chella Perumal Palanisamy et al. Am J Cancer Res. .

Abstract

Ovarian cancer (OC) accounts for the highest tumor-related mortality among the gynecologic malignancies. Most of the OC patients diagnosed with advanced-stage (III and IV) this situation creates panic and provokes an emergency to discover a new therapeutic strategy. Plants that possess medicinal properties are gaining attention as they are enriched with various chemical compounds that are potential to treat various diseases. It is a prolonged process to provide innovative and significant leads against a range of pharmacological targets for a human disease management system. Though challenges and difficulties are faced in the development of a new drug, the emergence of combinatorial chemistry is providing a new ray of hope and also, the executed effort in discovering the drug, and a chemical compound has been remarkably successful. This review discussed the role of medicinal plants that are native of South Africa in treating the Ovarian Cancer and in drug discovery.

Keywords: Ovarian cancer; anti-ovarian cancer activity; drug development; south african medicinal plants.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Modern drug discovery and development from the medicinal plant.
Figure 2
Figure 2
Anti-ovarian cancer activity of South African medicinal plants.
Figure 3
Figure 3
Anti-ovarian cancer potential of South African medicinal plants.
See this image and copyright information in PMC

References

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