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Case Reports
. 2021 Jun 2;13(6):e15392.
doi: 10.7759/cureus.15392.

Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Ryan T Ngo  1 , Amanda L Webb McAdams  1 , Anthony Furiato  1
Affiliations
Case Reports

Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Ryan T Ngo et al. Cureus. .

Abstract

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

Keywords: acute myeloid leukemia; blast crisis; hematologic malignancies; hyperleukocytosis; leukostasis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Chest X-ray
The image shows mild pulmonary edema
See this image and copyright information in PMC

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