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. 2021 May 20:8:681232.
doi: 10.3389/fmed.2021.681232. eCollection 2021.

Prevalence of Sarcopenia and Its Association With Diabetes: A Meta-Analysis of Community-Dwelling Asian Population

Seung Min Chung  1 , Jun Sung Moon  1 , Min Cheol Chang  2
Affiliations

Prevalence of Sarcopenia and Its Association With Diabetes: A Meta-Analysis of Community-Dwelling Asian Population

Seung Min Chung et al. Front Med (Lausanne). .

Abstract

Purpose: Sarcopenia is a major disease affecting mortality and quality of life in the elderly population. We performed a meta-analysis of studies on the community-dwelling population to investigate the prevalence of sarcopenia and its association with diabetes. Methods: Databases were searched for studies published up to February 3, 2021, reporting the prevalence of sarcopenia in patients with and without diabetes. Data extraction and quality assessment were performed according to the Newcastle-Ottawa scale. Results: Six articles were included in the systematic review. All the patients were Asian, aged ≥60 years (women 53.4%), and the diabetic and non-diabetic population was 1,537 and 5,485, respectively. In all six studies, the Asian Working Group for Sarcopenia criteria were used to diagnose sarcopenia. The prevalence of sarcopenia was 15.9% in diabetics and 10.8% in non-diabetics. Diabetics showed a significantly higher risk of sarcopenia than non-diabetics (pooled OR = 1.518, 95% CI = 1.110 to 2.076, Z-value = 2.611, p = 0.009). Conclusion: Among the Asian community-dwelling geriatric population, the prevalence of sarcopenia was significantly higher in diabetics than in non-diabetics. These results suggest that strategies for the management of sarcopenia are required in Asian elderly patients, especially with diabetes.

Keywords: diabetes mellitus; geriatrics; meta-analysis; prevalence; sarcopenia; type 2.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flow chart depicting the search results of the meta-analysis.
Figure 2
Figure 2
Results of the meta-analysis on sarcopenia prevalence among the (A) diabetes population and that among the (B) non-diabetes population.
Figure 3
Figure 3
Results of the meta-analysis on the difference in the risk of sarcopenia between the diabetes population and the non-diabetes population.
Figure 4
Figure 4
Graphic funnel plots of the included studies (A), diabetes population vs. non-diabetic population; (B), prevalence of sarcopenia among the diabetes population; (C), prevalence of sarcopenia among the non-diabetic population.
See this image and copyright information in PMC

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