SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility
- PMID: 34095871
- PMCID: PMC8169568
- DOI: 10.1016/j.xfre.2021.05.010
SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility
Abstract
Several reports claim that the purported similarity between syncytin-1 and the SARS-CoV-2 spike protein may induce immune cross-reactivity resulting in female sterility. We used frozen embryo transfer as a model for comparing the implantation rates between SARS-CoV-2 vaccine seropositive, infection seropositive, and seronegative women. No difference was found in serum hCG documented implantation rates or sustained implantation rates between the three groups. Reports claiming that COVID-19 vaccines or illness cause female sterility are unfounded.
Keywords: COVID-19; COVID-19 vaccination; SARS-CoV-2; implantation; spike protein; synctin-1.
© 2021 Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.
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