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. 2021 Jun 29;50(25):8820-8830.
doi: 10.1039/d1dt00648g.

Dual sensing of methionine and aspartic acid in aqueous medium by a quinoline-based fluorescent probe

C Elamathi  1 , R J Butcher  2 , A Mohankumar  3 , P Sundararaj  3 , K P Elango  4 , P Kalaivani  5 , R Prabhakaran  1
Affiliations

Dual sensing of methionine and aspartic acid in aqueous medium by a quinoline-based fluorescent probe

C Elamathi et al. Dalton Trans. .

Abstract

A quinoline-based Schiff base sensor, 6-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxaldehyde-4(N)-phenylsemicarbazone (6MPS), has been developed for selective sensing of methionine and aspartic acid in aqueous medium through "on-off-on" type selective detection of copper ion. Fluorescence imaging of 6MPS, 6MPSC, 6MPSCN, 6MPSC-met, 6MPSCN-met, 6MPSC-asp and 6MPSCN-asp has been successfully demonstrated, in which the sensing probes 6MPSC-met, 6MPSCN-met, 6MPSC-asp and 6MPSCN-asp displayed bright green fluorescence in both in vitro and in vivo live cells.

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