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Comparative Study
. 1988 May;7(5):483-6.
doi: 10.3109/02713688809031801.

Comparison of conjunctival and corneal surface areas in rabbit and human

M A Watsky  1 , M M Jablonski, H F Edelhauser
Affiliations
Comparative Study

Comparison of conjunctival and corneal surface areas in rabbit and human

M A Watsky et al. Curr Eye Res. 1988 May.

Abstract

This comparative study shows the surface area ratio of conjunctiva to cornea to be two times larger in humans than in rabbits. This large heretofore unrecognized interspecies difference may affect the applicability of drug pharmacokinetic data obtained using rabbit models and should be taken into consideration in topical drug development and future comparative drug penetration studies between rabbit and man.

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