Correlates of methamphetamine use severity among patients receiving methadone maintenance treatment for opioid use disorder in Vietnam

doi:10.1016/j.jsat.2021.108461

Review

. 2022 Jan:132:108461.

doi: 10.1016/j.jsat.2021.108461. Epub 2021 May 7.

Correlates of methamphetamine use severity among patients receiving methadone maintenance treatment for opioid use disorder in Vietnam

Le Minh Giang¹, Michael J Li², Chukwuemeka N Okafor³, Nguyen Bich Diep⁴, Steven J Shoptaw²

Affiliations

¹ Center for Training and Research on Substance Abuse-HIV, Hanoi Medical University, Hanoi, Viet Nam. Electronic address: leminhgiang@hmu.edu.vn.
² Center for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, United States of America.
³ Department of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, United States of America.
⁴ Center for Training and Research on Substance Abuse-HIV, Hanoi Medical University, Hanoi, Viet Nam.

PMID: 34098204
PMCID: PMC8572314
DOI: 10.1016/j.jsat.2021.108461

Review

Correlates of methamphetamine use severity among patients receiving methadone maintenance treatment for opioid use disorder in Vietnam

Le Minh Giang et al. J Subst Abuse Treat. 2022 Jan.

. 2022 Jan:132:108461.

doi: 10.1016/j.jsat.2021.108461. Epub 2021 May 7.

Authors

Le Minh Giang¹, Michael J Li², Chukwuemeka N Okafor³, Nguyen Bich Diep⁴, Steven J Shoptaw²

Affiliations

¹ Center for Training and Research on Substance Abuse-HIV, Hanoi Medical University, Hanoi, Viet Nam. Electronic address: leminhgiang@hmu.edu.vn.
² Center for Behavioral and Addiction Medicine, Department of Family Medicine, University of California, Los Angeles, United States of America.
³ Department of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, United States of America.
⁴ Center for Training and Research on Substance Abuse-HIV, Hanoi Medical University, Hanoi, Viet Nam.

PMID: 34098204
PMCID: PMC8572314
DOI: 10.1016/j.jsat.2021.108461

Abstract

Objectives: To assess the severity of methamphetamine use among methadone maintenance treatment (MMT) patients in Vietnam with opioid use disorder and concurrent methamphetamine use, and to identify risk factors associated with higher severity of methamphetamine use.

Methods: We used survey data and medical record abstractions from 428 people with opioid use disorder who also use methamphetamine while partaking in methadone treatment in five clinics in Hanoi, Vietnam. We used multinomial logistic regression to assess other risk factors and problems associated with high methamphetamine use severity.

Results: Those who reported injecting heroin in the past 3 months (AOR = 4.05, 95% CI [1.30, 12.55], p = 0.02), having a longer history of lifetime heroin use (AOR = 1.13, 95% CI [1.03, 1.24], p < 0.01), and having higher cravings (AOR = 1.97, 95% CI [1.31, 2.98], p < 0.01) and fatigue (AOR = 1.25, 95% CI [0.96, 1.61], p = 0.09) related to methamphetamine withdrawal had greater odds of high methamphetamine use severity. One of five clinics had a significantly higher percentage of methamphetamine use severity than others.

Conclusion: Successful MMT in patients with opioid use disorder in Vietnam may additionally require methamphetamine-focused screening and intervention.

Keywords: Heroin; Methadone maintenance treatment; Methamphetamine; Opioid; Polysubstance use; Vietnam.

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Conflict of interest statement

Conflicts of interest:

The authors report no conflicts of interest.

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References

1. Al-Tayyib A, Koester S, Langegger S, & Raville L (2017). Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern. Substance Use & Misuse, 52(8), 1051–1058. 10.1080/10826084.2016.1271432 - DOI - PMC - PubMed
1. Betts KS, McIlwraith F, Dietze P, Whittaker E, Burns L, Cogger S, & Alati R (2015). Can differences in the type, nature or amount of polysubstance use explain the increased risk of non-fatal overdose among psychologically distressed people who inject drugs? Drug and Alcohol Dependence, 154, 76–84. 10.1016/j.drugalcdep.2015.06.020 - DOI - PubMed
1. Dong H, Yang M, Liu L, Zhang C, Liu M, Shen Y, Liu H, & Hao W (2017). Comparison of demographic characteristics and psychiatric comorbidity among methamphetamine-, heroin- and methamphetamine-heroin co- dependent males in Hunan, China. BMC Psychiatry, 17(1), 183. 10.1186/s12888-017-1346-7 - DOI - PMC - PubMed
1. Ellis MS, Kasper ZA, & Cicero TJ (2018). Twin epidemics: The surging rise of methamphetamine use in chronic opioid users. Drug and Alcohol Dependence, 193, 14–20. 10.1016/j.drugalcdep.2018.08.029 - DOI - PubMed
1. Feelemyer J, Duong Thi H, Khuê Pham M, Hoang Thi G, Thi Tuyet Thanh N, Thi Hai Oanh K, Arasteh K, Moles JP, Vu Hai V, Vallo R, Quillet C, Rapoud D, Michel L, Hammett T, Laureillard D, Nagot N, & Des Jarlais D (2018). Increased methamphetamine use among persons who inject drugs in Hai Phong, Vietnam, and the association with injection and sexual risk behaviors. Journal of Psychoactive Drugs, 50(5), 382–389. - PMC - PubMed

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[1] Al-Tayyib A, Koester S, Langegger S, & Raville L (2017). Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern. Substance Use & Misuse, 52(8), 1051–1058. 10.1080/10826084.2016.1271432 - DOI - PMC - PubMed

[2] Al-Tayyib A, Koester S, Langegger S, & Raville L (2017). Heroin and Methamphetamine Injection: An Emerging Drug Use Pattern. Substance Use & Misuse, 52(8), 1051–1058. 10.1080/10826084.2016.1271432 - DOI - PMC - PubMed

[3] Betts KS, McIlwraith F, Dietze P, Whittaker E, Burns L, Cogger S, & Alati R (2015). Can differences in the type, nature or amount of polysubstance use explain the increased risk of non-fatal overdose among psychologically distressed people who inject drugs? Drug and Alcohol Dependence, 154, 76–84. 10.1016/j.drugalcdep.2015.06.020 - DOI - PubMed

[4] Betts KS, McIlwraith F, Dietze P, Whittaker E, Burns L, Cogger S, & Alati R (2015). Can differences in the type, nature or amount of polysubstance use explain the increased risk of non-fatal overdose among psychologically distressed people who inject drugs? Drug and Alcohol Dependence, 154, 76–84. 10.1016/j.drugalcdep.2015.06.020 - DOI - PubMed

[5] Dong H, Yang M, Liu L, Zhang C, Liu M, Shen Y, Liu H, & Hao W (2017). Comparison of demographic characteristics and psychiatric comorbidity among methamphetamine-, heroin- and methamphetamine-heroin co- dependent males in Hunan, China. BMC Psychiatry, 17(1), 183. 10.1186/s12888-017-1346-7 - DOI - PMC - PubMed

[6] Dong H, Yang M, Liu L, Zhang C, Liu M, Shen Y, Liu H, & Hao W (2017). Comparison of demographic characteristics and psychiatric comorbidity among methamphetamine-, heroin- and methamphetamine-heroin co- dependent males in Hunan, China. BMC Psychiatry, 17(1), 183. 10.1186/s12888-017-1346-7 - DOI - PMC - PubMed

[7] Ellis MS, Kasper ZA, & Cicero TJ (2018). Twin epidemics: The surging rise of methamphetamine use in chronic opioid users. Drug and Alcohol Dependence, 193, 14–20. 10.1016/j.drugalcdep.2018.08.029 - DOI - PubMed

[8] Ellis MS, Kasper ZA, & Cicero TJ (2018). Twin epidemics: The surging rise of methamphetamine use in chronic opioid users. Drug and Alcohol Dependence, 193, 14–20. 10.1016/j.drugalcdep.2018.08.029 - DOI - PubMed

[9] Feelemyer J, Duong Thi H, Khuê Pham M, Hoang Thi G, Thi Tuyet Thanh N, Thi Hai Oanh K, Arasteh K, Moles JP, Vu Hai V, Vallo R, Quillet C, Rapoud D, Michel L, Hammett T, Laureillard D, Nagot N, & Des Jarlais D (2018). Increased methamphetamine use among persons who inject drugs in Hai Phong, Vietnam, and the association with injection and sexual risk behaviors. Journal of Psychoactive Drugs, 50(5), 382–389. - PMC - PubMed

[10] Feelemyer J, Duong Thi H, Khuê Pham M, Hoang Thi G, Thi Tuyet Thanh N, Thi Hai Oanh K, Arasteh K, Moles JP, Vu Hai V, Vallo R, Quillet C, Rapoud D, Michel L, Hammett T, Laureillard D, Nagot N, & Des Jarlais D (2018). Increased methamphetamine use among persons who inject drugs in Hai Phong, Vietnam, and the association with injection and sexual risk behaviors. Journal of Psychoactive Drugs, 50(5), 382–389. - PMC - PubMed

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Correlates of methamphetamine use severity among patients receiving methadone maintenance treatment for opioid use disorder in Vietnam

Affiliations

Correlates of methamphetamine use severity among patients receiving methadone maintenance treatment for opioid use disorder in Vietnam

Authors

Affiliations

Abstract

Conflict of interest statement

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Cited by

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Abstract

Conflict of interest statement

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