Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jun;159(6):e361-e364.
doi: 10.1016/j.chest.2020.11.064.

Pulmonary Vein Thrombosis in COVID-19

Stephanie A Goddard  1 , Daniel Q Tran  2 , Michael F Chan  2 , Michelle N Honda  2 , Mandy C Weidenhaft  2 , Benjamin L Triche  2
Affiliations
Case Reports

Pulmonary Vein Thrombosis in COVID-19

Stephanie A Goddard et al. Chest. 2021 Jun.

Abstract

Research on COVID-19, the cause of a rapidly worsening pandemic, has led to the observation of laboratory derangements such as a propensity towards a hypercoagulable state. However, there are currently no reports on the incidence of pulmonary venous thrombosis in the setting of COVID-19. We report a case in which follow-up chest CT scans revealed an expansile filling defect in a branch of the right inferior pulmonary vein, which is consistent with pulmonary venous thrombosis. Our objective was to provide insight into an uncommon sequela of COVID-19 and consequently garner increased clinical suspicion for pulmonary VTE during hospitalization.

Keywords: COVID-19; imaging; pulmonary; thrombosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Axial CT scan of the chest shows features that are consistent with COVID-19: scattered peribronchovascular and peripheral mid to lower lung predominant ground-glass opacities and consolidations.
Figure 2
Figure 2
Axial contrast enhanced CT images of the chest: nonocclusive filling defect within the lateral basilar segmental pulmonary artery (white arrow), which is consistent with pulmonary arterial thromboembolic disease.
Figure 3
Figure 3
A, Axial, B, coronal, and C, sagittal contrast enhanced CT images of the chest: filling defect with focal distention of a branch of the right inferior pulmonary vein (white arrows), consistent with occlusive pulmonary venous thrombosis.
See this image and copyright information in PMC

References

    1. Dong E., Du H., Gardner L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Inf Dis. 2020;20(5):533–534. - PMC - PubMed
    1. Suxin W., Yi X., Wei F., et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020;92(7):797–806. - PMC - PubMed
    1. Zhang Y., Cao W., Xiao M., et al. Clinical and coagulation characteristics of 7 patients with critical COVID 2019 pneumonia and acro-ischemia. Zhonghua Xue Ye Xue Za Zhi. 2020;41(0):E006. - PubMed
    1. Kim N.H., Roldan C.A., Shively B.K., et al. Pulmonary vein thrombosis. Chest. 1993;104(2):624–626. - PubMed
    1. Chaaya G., Vishnubhotla P. Pulmonary vein thrombosis: a recent systematic review. Cureus. 2017;9(1):e993. - PMC - PubMed

Publication types