Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jul;68(3):330-333.
doi: 10.1016/j.ijtb.2020.11.003. Epub 2020 Nov 10.

Post covid 19 pulmonary fibrosis. Is it real threat?

Deependra Kumar Rai  1 , Priya Sharma  2 , Rahul Kumar  2
Affiliations
Review

Post covid 19 pulmonary fibrosis. Is it real threat?

Deependra Kumar Rai et al. Indian J Tuberc. 2021 Jul.

Abstract

After the COVID-19 outbreak, increasing number of patients worldwide who have survived COVID-19 continue to battle the symptoms of the illness, long after they have been clinically tested negative for the disease. As we battle through this pandemic, the challenging part is to manage COVID-19 sequelae which may vary from fatigue and body aches to lung fibrosis. This review addresses underlying mechanism, risk factors, course of disease and treatment option for post covid pulmonary fibrosis. Elderly patient who require ICU care and mechanical ventilation are at the highest risk to develop lung fibrosis. Currently, no fully proven options are available for the treatment of post inflammatory COVID 19 pulmonary fibrosis.

Keywords: ARDS; Antifibrotic; Covid 19; Pulmonary fibrosis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest The authors have none to declare.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Zhu N., Zhang D., Wang W. China novel coronavirus investigating and research team. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–733. - PMC - PubMed
    1. Carfì A., Bernabei R., Landi F. For the Gemelli against COVID-19 post-acute care study group. Persistent symptoms in patients after acute COVID-19. J Am Med Assoc. 2020;324(6):603–605. - PMC - PubMed
    1. Istituto Superiore Sanità . 2020. Sorveglianza Integrata COVID-19 in Italia.
    1. Liu J., Zheng X., Tong Q. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV. J Med Virol. 2020;92(5):491–494. - PMC - PubMed
    1. Burnham E.L., Janssen W.J., Riches D.W., Moss M., Downey G.P. The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance. Eur Respir J. 2014;43:276–285. - PMC - PubMed