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Case Reports
. 1988 Jun;147(5):532-5.
doi: 10.1007/BF00441984.

Male pseudohermaphroditism due to 5 alpha-reductase deficiency in a Swedish family

S A Ivarsson  1 , M D Nielsen, T Lindberg
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Case Reports

Male pseudohermaphroditism due to 5 alpha-reductase deficiency in a Swedish family

S A Ivarsson et al. Eur J Pediatr. 1988 Jun.

Abstract

Three sibs with an inherited form of male pseudohermaphroditism are described. They were all born with ambiguous external genitalia but no diagnosis of a possible enzyme defect was made during childhood. First seen at the ages of 16, 14 and 10 years respectively, they were investigated in order to establish the pathogenetic nature of the disorder. Serum concentrations of testosterone and dihydrotestosterone before and after stimulation with human chorionic gonadotropin suggested 5 alpha-reductase deficiency. Measurement of steroid metabolites in urine confirmed this diagnosis. It is essential to recognize this condition in order to decide the sex of rearing of the children.

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References

    1. N Engl J Med. 1974 Oct 31;291(18):938-44 - PubMed
    1. Clin Genet. 1972;3(1):1-26 - PubMed
    1. Clin Chim Acta. 1976 Jun 1;69(2):267-83 - PubMed
    1. N Engl J Med. 1974 Oct 31;291(18):944-9 - PubMed
    1. Clin Chim Acta. 1980 Nov 6;107(3):231-43 - PubMed

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