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Review
. 2021 Aug;92(8):762-772.
doi: 10.1007/s00115-021-01138-5. Epub 2021 Jun 7.

[Border areas of thrombectomy]

[Article in German]
Marios-Nikos Psychogios  1 , Alex Brehm  2 , Peter Sporns  2 , Leo H Bonati  3
Affiliations
Review

[Border areas of thrombectomy]

[Article in German]
Marios-Nikos Psychogios et al. Nervenarzt. 2021 Aug.

Abstract
in English, German

Mechanical thrombectomy (MT) has become the standard procedure in the treatment of patients with acute ischemic stroke (AIS) due to occlusion of a large proximal cerebral artery of the anterior circulation. Nevertheless, according to the current guidelines large patient collectives are still excluded from this highly effective treatment method. Therefore, this article gives an overview of possible extensions of the indications for treatment with MT. For example, patients in the extended time window with distal occlusions, with large infarct cores and also for very old (90+ years) or young (0-17 years) patients. Furthermore, we discuss recent developments in the interventional treatment of stroke, such as new triage concepts or the question whether an additional intravenous thrombolysis is necessary in patients with MT. We conclude with our own estimations for the discussed indications for treatment based on our clinical experience and the current literature.

Die mechanische Thrombektomie (MT) hat sich als Standardverfahren für die Behandlung akuter ischämischer Schlaganfälle aufgrund eines Verschlusses einer großen, proximalen Hirnarterie der vorderen Zirkulation etabliert. Dennoch sind nach aktuellen Guidelines noch große Patientenkollektive von dieser hocheffektiven Behandlungsmethode ausgeschlossen. Diese Arbeit gibt daher einen Überblick über mögliche Erweiterungen der Behandlungsindikationen für die MT, wie z. B. Patienten im erweiterten Zeitfenster, mit distalen Verschlüssen, mit großem Infarktkern oder auch für sehr alte (> 90 Jahre) und junge (0–17 Jahre) Patienten. Zusätzlich besprechen wir neue Entwicklungen in der interventionellen Behandlung von Schlaganfällen, wie z. B. neue Triage-Konzepte oder die Fragestellung, ob die zusätzliche intravenöse Thrombolyse bei MT-Patienten notwendig ist. Abschließend geben wir für die besprochenen Behandlungsindikationen unsere Einschätzungen basierend auf der aktuellen Literatur und unserer klinischen Erfahrung.

Keywords: Endovascular treatment; Ischemic stroke; Mechanical thrombectomy; Treatment indications; Vascular occlusion.

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References

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