Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jun 8;9(6).
doi: 10.2106/JBJS.RVW.20.00171.

Hip Arthroplasty in Patients with Osteogenesis Imperfecta

Allan Roy Sekeitto  1 , Kaeriann van der Jagt  1 , Nkhodiseni Sikhauli  1 , Lipalo Mokete  1 , Alban Gerard Bowers  2 , Dick Ronald van der Jagt  1
Affiliations
Review

Hip Arthroplasty in Patients with Osteogenesis Imperfecta

Allan Roy Sekeitto et al. JBJS Rev. .

Abstract

»: Osteogenesis imperfecta (OI) is a rare congenital disorder that affects connective tissue.

»: Modern medicine has mitigated the mortality that is associated with OI, allowing patients to live a near-normal life span.

»: The degenerative process in OI is probably accelerated because of subclinical intra-articular fractures, joint laxity, and distorted femoral and acetabular anatomy.

»: Total hip arthroplasty is seldom performed in patients with OI; it is technically difficult due to bone fragility, deformity, soft-tissue alteration, acetabular protrusion, the risk of intraoperative and postoperative fractures, and joint laxity.

»: This review highlights that patients with OI need hip arthroplasty procedures at an early age and that early revision surgery can be expected. New-generation uncemented implants may improve implant survivorship.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The authors indicated that no external funding was received for any aspect of this work. On the Disclosure of Potential Conflicts of Interest forms, which are provided with the online version of the article, one or more of the authors checked “yes” to indicate that the author had a relevant financial relationship in the biomedical arena outside the submitted work (http://links.lww.com/JBJSREV/A698).

References

    1. Monti E, Mottes M, Fraschini P, Brunelli P, Forlino A, Venturi G, Doro F, Perlini S, Cavarzere P, Antoniazzi F. Current and emerging treatments for the management of osteogenesis imperfecta. Ther Clin Risk Manag. 2010 Sep 7;6:367-81.
    1. Sanz-Ruiz P, Villanueva-Martinez M, Calvo-Haro JA, Carbó-Laso E, Vaquero-Martín J. Total femur arthroplasty for revision hip failure in osteogenesis imperfecta: limits of biology. Arthroplast Today. 2017 Mar 6;3(3):154-9.
    1. Liporace FA, Yoon RS, Frank MA, Maurer JP, Gaines RJ. Single-stage total hip arthroplasty and fracture fixation for a both column acetabular fracture in type I osteogenesis imperfecta. Injury. 2011 Oct;42(10):1184-7. Epub 2011 Jun 1.
    1. Roberts TT, Cepela DJ, Uhl RL, Lozman J. Orthopaedic considerations for the adult with osteogenesis imperfecta. J Am Acad Orthop Surg. 2016 May;24(5):298-308.
    1. Ramaswamy R, Kosashvili Y, Cameron H. Bilateral total hip replacement in osteogenesis imperfecta with hyperplastic callus. J Bone Joint Surg Br. 2009 Jun;91(6):812-4.

LinkOut - more resources