Can Paclitaxel Coated Balloons Have a Deep Impact on Critical Limb Ischemia?
- PMID: 34101768
- PMCID: PMC8165196
- DOI: 10.1016/j.jacbts.2021.04.003
Can Paclitaxel Coated Balloons Have a Deep Impact on Critical Limb Ischemia?
Keywords: angioplasty; below-the-knee arteries; chronic limb-threatening ischemia; critical limb ischemia; drug-coated balloon; paclitaxel; peripheral artery disease.
Conflict of interest statement
Dr. Parikh has received institutional research support from Abbott Vascular, Boston Scientific, Shockwave Medical, Surmodics, TriReme, and Veryan Medical; served as a noncompensated advisor to Abbott Vascular, Boston Scientific, Cordis, CSI, Janssen, Medtronic, and Philips; and served as consultant to Abiomed, Inari, Penumbra, and Terumo. Dr. Finn has received honoraria from Janssen.
Comment on
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  Downstream Paclitaxel Released Following Drug-Coated Balloon Inflation and Distal Limb Wound Healing in Swine.JACC Basic Transl Sci. 2021 Mar 31;6(5):416-427. doi: 10.1016/j.jacbts.2021.01.012. eCollection 2021 May. JACC Basic Transl Sci. 2021. PMID: 34095632 Free PMC article.
References
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    - Nordanstig J., James S., Andersson M. Mortality with paclitaxel-coated devices in peripheral artery disease. N Engl J Med. 2020;383:2538–2546. - PubMed
 
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    - Katsanos K., Spiliopoulos S., Kitrou P. Risk of death and amputation with use of paclitaxel-coated balloons in the infrapopliteal arteries for treatment of critical limb ischemia: a systematic review and meta-analysis of randomized controlled trials. J Vasc Interv Radiol. 2020;31:202–212. - PubMed
 
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    - Zeller T., Baumgartner I., Scheinert D. Drug-eluting balloon versus standard balloon angioplasty for infrapopliteal arterial revascularization in critical limb ischemia: 12-month results from the IN.PACT DEEP randomized trial. J Am Coll Cardiol. 2014;64:1568–1576. - PubMed
 
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