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. 2021 Sep;11(5):571-581.
doi: 10.2217/pmt-2020-0089. Epub 2021 Jun 9.

The effect of obesity on pain severity and pain interference

Jade I Basem  1 , Robert S White  1 , Stephanie A Chen  2 , Elizabeth Mauer  3 , Michele L Steinkamp  1 , Charles E Inturrisi  4 , Lisa R Witkin  1
Affiliations

The effect of obesity on pain severity and pain interference

Jade I Basem et al. Pain Manag. 2021 Sep.

Abstract

Aim: Obesity is one of the most prevalent comorbidities associated with chronic pain, which can severely interfere with daily living and increase utilization of clinical resources. We hypothesized that a higher level of obesity, measured by BMI, would be associated with increased pain severity (intensity) and interference (pain related disability). Materials & methods: Participant data was pulled from a multisite chronic pain outpatient database and categorized based on BMI. Results: A total of 2509 patients were included in the study. We found significant differences between BMI groups for all pain severity scores (worst, least, average, current) and total pain interference score. Obese patients had significantly higher scores than normal weight patients. Conclusion: We found obesity to be associated with increased pain severity and pain interference.

Keywords: chronic pain; obesity; outcome assessment; pain management; pain medicine.

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Conflict of interest statement

Financial & competing interests disclosure

CE Inturrisi receives compensation as described in a 2017 license agreement between CE Inturrisi (and P Manfredi) and Relmada Therapeutics, Inc. for the development of compounds (including d-methadone) for the treatment of depression. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

References

    1. Gaskin DJ, Richard P. The economic costs of pain in the United States. J. Pain 13(8), 715–724 (2012). - PubMed
    1. Relieving pain in America: a blueprint for transforming prevention, care, education, and research. Mil. Med. 181(5), 397–399 (2016). https://academic.oup.com/milmed/article/181/5/397/4158290 - PubMed
    1. Nahin RL. Estimates of pain prevalence and severity in adults: United States, 2012. J. Pain 16(8), 769–780 (2015). - PMC - PubMed
    1. Daubresse M, Chang HY, Yu Y et al. Ambulatory diagnosis and treatment of nonmalignant pain in the United States, 2000–2010. Med. Care 51(10), 870–878 (2013). - PMC - PubMed
    1. White RS, Jiang J, Hall CB et al. Higher perceived stress scale scores are associated with higher pain intensity and pain interference levels in older adults. J. Am. Geriatr. Soc. 62(12), 2350–2356 (2014). - PMC - PubMed