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. 2021 Jun;44(5):363-371.
doi: 10.1016/j.jmpt.2021.03.004. Epub 2021 Jun 5.

Effects of Thrust Magnitude and Duration on Immediate Postspinal Manipulation Trunk Muscle Spindle Responses

Carla R Lima  1 , Randall S Sozio  2 , AaMarryah C Law  3 , Alicia J Nelson  3 , Harshvardhan Singh  4 , Christopher P Hurt  4 , Peng Li  5 , William R Reed  6
Affiliations

Effects of Thrust Magnitude and Duration on Immediate Postspinal Manipulation Trunk Muscle Spindle Responses

Carla R Lima et al. J Manipulative Physiol Ther. 2021 Jun.

Abstract

Objective: The purpose of this study was to characterize trunk muscle spindle responses immediately after high-velocity, low-amplitude spinal manipulation (HVLA-SM) delivered at various thrust magnitudes and thrust durations.

Methods: Secondary analysis from multiple studies involving anesthetized adult cats (N = 70; 2.3-6.0 kg) receiving L6 HVLA-SM. Muscle spindle afferent recordings were obtained from L6 dorsal rootlets before, during, and immediately after HVLA-SM. L6 HVLA-SM was delivered posteriorly-to-anteriorly using a feedback motor with peak thrust magnitudes of 25%, 55%, and 85% of cat body weight (BW) and thrust durations of 25, 50, 75, 100, 150, 200, and 250 ms. Time to the first action potential and muscle spindle discharge frequency at 1 and 2 seconds post-HVLA-SM were determined.

Results: A significant association between HVLA-SM thrust magnitude and immediate (≤2 s) muscle spindle response was found (P < .001). For non-control thrust magnitude, pairwise comparisons (25%, 55%, 85% BW), 55% BW thrust magnitude had the most consistent effect on immediate post-HVLA-SM discharge outcomes (false discovery rate < 0.05). No significant association was found between thrust duration and immediate post-HVLA-SM muscle spindle response (P > .05).

Conclusion: The present study found that HVLA-SM thrust magnitudes delivered at 55% BW were more likely to affect immediate (≤2 s) post-HVLA-SM muscle spindle response.

Keywords: Back Muscles; Manipulation, Spinal; Muscle Spindles; Musculoskeletal Manipulations; Neurophysiology.

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Conflict of interest statement

Conflicts of interest

None declared

References

    1. Global GBD R., regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1923–94. Epub 2018/11/30. doi: 10.1016/s0140-6736(18)32225-6. - DOI - PMC - PubMed
    1. Chou R, Huffman LH. Medications for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline. Annals of internal medicine. 2007;147(7):505–14. Epub 2007/10/03. doi: 10.7326/0003-4819-147-7-200710020-00008. - DOI - PubMed
    1. Chou R, Atlas SJ, Stanos SP, Rosenquist RW. Nonsurgical interventional therapies for low back pain: a review of the evidence for an American Pain Society clinical practice guideline. Spine. 2009;34(10):1078–93. Epub 2009/04/14. doi: 10.1097/BRS.0b013e3181a103b1. - DOI - PubMed
    1. Katz N, Borenstein DG, Birbara C, Bramson C, Nemeth MA, Smith MD, et al. Efficacy and safety of tanezumab in the treatment of chronic low back pain. Pain. 2011;152(10):2248–58. Epub 2011/06/24. doi: 10.1016/j.pain.2011.05.003. - DOI - PubMed
    1. Deyo RA. The Role of Spinal Manipulation in the Treatment of Low Back Pain. JAMA. 2017;317(14):1418–9. doi: 10.1001/jama.2017.3085 %J JAMA. - PubMed

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