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. 2021 Jan 28;9(1):70-83.
doi: 10.1080/21642850.2021.1873140.

Mental health and quality of life of patients undergoing hematopoietic stem cell transplantation (HSCT) prior to hospitalization: a cross-sectional complete state health study

Maya Corman  1 , Marie-Thérèse Rubio  2 , Aurélie Cabrespine  3 , Isabelle Brindel  4 , Jacques-Olivier Bay  3 , Régis Peffault De La Tour  4 , Michaël Dambrun  1
Affiliations

Mental health and quality of life of patients undergoing hematopoietic stem cell transplantation (HSCT) prior to hospitalization: a cross-sectional complete state health study

Maya Corman et al. Health Psychol Behav Med. .

Abstract

Objective: The main goal of this cross-sectional study was to examine the relationships between negative/positive psychological dispositions, mental health, and quality of life (QoL) prior to hospitalization among patients undergoing hematopoietic stem cell transplantation (HSCT).

Method: A total of 187 patients (Mage = 52.07 years) completed a questionnaire 19.6 days before an allograft. Several positive psychological dispositions (i.e. mindfulness, optimism, and acceptance) and a negative psychological disposition (i.e. experiential avoidance) were assessed. Our dependent variables were mental health (i.e. happiness, depression, and anxiety) and QoL.

Results: In the sample, 56.8% of patients were characterized by an impaired QoL and 56.9% and 21% had, respectively, anxiety and depression levels above the critical threshold (i.e. a score above seven on the Hospital Anxiety and Depression Scale). Anxiety, depression, and happiness were significantly related to the mental component of QoL, whereas physical QoL was only related to depression and happiness. Providing additional support for a complete state health approach, several positive and negative psychological dispositions (i.e. optimism, acceptance, and experiential avoidance) were robustly related to mental illness/wellness and QoL.

Conclusions: These results highlight the importance of improving psychological health and QoL among HSCT patients prior to hospitalization by both promoting positive psychological and health factors and alleviating negative ones.

Keywords: Complete state model of health (CSMH); anxiety; depression; happiness; negative and positive psychological dispositions; quality of life.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

References

    1. Aguirre-Camacho, A., Pelletier, G., González-Márquez, A., Blanco-Donoso, L. M., García-Borreguero, P., & Moreno-Jiménez, B. (2017). The relevance of experiential avoidance in breast cancer distress: Insights from a psychological group intervention. Psycho-Oncology, 26(4), 469–475. - PubMed
    1. Allart-Vorelli, P., Porro, B., Baguet, F., Michel, A., & Cousson-Gélie, F. (2015). Haematological cancer and quality of life: A systematic literature review. Blood Cancer Journal, 5(4), e305–e305. - PMC - PubMed
    1. Amonoo, H., Brown, L., Scheu, C., Millstein, R., Pirl, W., & Vitagliano, H. (2019). Positive psychological experiences in allogeneic hematopoietic stem cell transplantation. Psycho-Oncology. doi:10.1002/pon.5128 - DOI - PubMed
    1. Artherholt, S., Hong, F., Berry, D., & Fann, J. (2014). Risk factors for depression in patients undergoing hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation, 20(7), 946–950. - PMC - PubMed
    1. Baer, R., Smith, G., Lykins, E., Button, D., Krietemeyer, J., & Sauer, S. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15(3), 329–342. - PubMed

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