Ovarian tumors orchestrate distinct cellular compositions
- PMID: 34107269
- DOI: 10.1016/j.immuni.2021.05.014
Ovarian tumors orchestrate distinct cellular compositions
Abstract
The determinants of T cell infiltration in tumors remain largely unknown. In a recent issue of Cancer Cell, Hornburg et al. use single-cell RNA sequencing to characterize the cellular compartments of the ovarian cancer microenvironment and shed light on how tumor, immune, and stromal cells interact and shape T cell infiltration.
Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.
Comment on
-
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer.Cancer Cell. 2021 Jul 12;39(7):928-944.e6. doi: 10.1016/j.ccell.2021.04.004. Epub 2021 May 6. Cancer Cell. 2021. PMID: 33961783
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical