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. 2021 Jun 9;21(1):218.
doi: 10.1186/s12883-021-02249-x.

Validity and reliability of the Georgian-language brief international cognitive assessment for multiple sclerosis (BICAMS)

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Validity and reliability of the Georgian-language brief international cognitive assessment for multiple sclerosis (BICAMS)

Nazibrola Botchorishvili et al. BMC Neurol. .

Abstract

Background: Cognitive impairment is one of the common features of multiple sclerosis (MS). Despite high prevalence, cognitive decline is often overlooked by neurologists. The Brief International Cognitive Assessment for MS (BICAMS) was therefore introduced by the international expert committee as a brief and effective tool for the assessment and monitoring of cognitive functions in patients with MS. The validity and reliability of BICAMS have been demonstrated in many countries. Our aim was to validate the BICAMS in Georgian patients with MS.

Methods: A total of 68 patients with MS and 68 matched controls were assessed by the Georgian-language BICAMS. All healthy controls and seven patients were re-evaluated with identical tests to assess retest reliability.

Results: In comparison to healthy controls, patients with MS performed significantly worse on all tests in the assessment battery. Test-retest reliability measures were good for all tests. The prevalence of cognitive impairment in patients with MS was 43%.

Conclusion: The Georgian-language BICAMS is a reliable and valid battery for the assessment of cognitive function in patients with MS.

Keywords: Brief International Cognitive Assessment in MS (BICAMS); Cognitive impairment; Georgian language; Multiple sclerosis; Validation.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Peterson LK, Fujinami RS. Inflammation, demyelination, neurodegeneration and neuroprotection in the pathogenesis of multiple sclerosis. J Neuroimmunol. 2007;184:37–44. doi: 10.1016/j.jneuroim.2006.11.015. - DOI - PMC - PubMed
    1. Filippi M, Bar-Or A, Piehl F, Preziosa P, Solari A, Vukusic S, et al. Multiple sclerosis. Nat Rev Dis. 2018;4:49. doi: 10.1038/s41572-018-0041-4. - DOI - PubMed
    1. Amato MP, Zipoli V, Portaccio E. Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies. J Neurol Sci. 2006;245:41–46. doi: 10.1016/j.jns.2005.08.019. - DOI - PubMed
    1. Benedict RH, Zivadinov R. Risk factors for and management of cognitive dysfunction in multiple sclerosis. Nat Reviews Neurol. 2011;7:332. doi: 10.1038/nrneurol.2011.61. - DOI - PubMed
    1. Denney DR, Sworowski LA, Lynch SG. Cognitive impairment in three subtypes of multiple sclerosis. Arch Clin Neuropsychol. 2005;20:967–981. doi: 10.1016/j.acn.2005.04.012. - DOI - PubMed

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