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Comment
. 2021 Jun 10;137(23):3163-3164.
doi: 10.1182/blood.2021011368.

Expect the unexpected

Affiliations
Comment

Expect the unexpected

Didier Blaise. Blood. .
No abstract available

Keywords: MARROW AND STEM CELL TRANSPLANTATION/organ specific toxicity: infectious; cytomegalovirus; retospective study.

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Conflict of interest statement

Conflict-of-interest disclosure: D.B. has received honoraria from Jazz Pharmaceuticals and expertise fees from Molmed.

Figures

None
Multivariate analyses of the combined impact of CMV serostatus, donor source, and PTCy on OS. See Figure 3B in the article by Goldsmith et al that begins on page 3291.

Comment on

  • Posttransplant cyclophosphamide is associated with increased cytomegalovirus infection: a CIBMTR analysis.
    Goldsmith SR, Abid MB, Auletta JJ, Bashey A, Beitinjaneh A, Castillo P, Chemaly RF, Chen M, Ciurea S, Dandoy CE, Díaz MÁ, Fuchs E, Ganguly S, Kanakry CG, Kanakry JA, Kim S, Komanduri KV, Krem MM, Lazarus HM, Liu H, Ljungman P, Masiarz R, Mulroney C, Nathan S, Nishihori T, Page KM, Perales MA, Taplitz R, Romee R, Riches M. Goldsmith SR, et al. Blood. 2021 Jun 10;137(23):3291-3305. doi: 10.1182/blood.2020009362. Blood. 2021. PMID: 33657221 Free PMC article. Clinical Trial.

References

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    1. Crocchiolo R, Castagna L, Furst S, et al. The patient’s CMV serological status affects clinical outcome after T-cell replete haplo-HSCT and post-transplant cyclophosphamide. Bone Marrow Transplant. 2016;51(8):1134-1136. - PubMed
    1. Teira P, Battiwalla M, Ramanathan M, et al. Early cytomegalovirus reactivation remains associated with increased transplant-related mortality in the current era: a CIBMTR analysis. Blood. 2016;127(20):2427-2438. - PMC - PubMed
    1. Passweg JR, Baldomero H, Chabannon C, et al; European Society for Blood and Marrow Transplantation (EBMT) . The EBMT activity survey on hematopoietic-cell transplantation and cellular therapy 2018: CAR-T’s come into focus. Bone Marrow Transplant. 2020;55(8):1604-1613. - PMC - PubMed
    1. D’Souza A, Fretham C, Lee SJ, et al. Current use of and trends in hematopoietic cell transplantation in the United States. Biol Blood Marrow Transplant. 2020;26(8):e177-e182. - PMC - PubMed