[Lorlatinib: a promising drug in the future treatment of advanced ALK-positive non-small-cell lung cancer]
- PMID: 34110434
- PMCID: PMC8219586
- DOI: 10.1007/s00066-021-01788-z
[Lorlatinib: a promising drug in the future treatment of advanced ALK-positive non-small-cell lung cancer]
Comment on
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First-Line Lorlatinib or Crizotinib in Advanced ALK-Positive Lung Cancer.N Engl J Med. 2020 Nov 19;383(21):2018-2029. doi: 10.1056/NEJMoa2027187. N Engl J Med. 2020. PMID: 33207094 Clinical Trial.
References
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- Christensen JG, Zou HY, Arango ME, Li Q, Lee JH, McDonnell SR, et al. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma. Mol Cancer Ther. 2007;6(12):3314–3322. doi: 10.1158/1535-7163.MCT-07-0365. - DOI - PubMed
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- Bauer TM, Shaw AT, Johnson ML, Navarro A, Gainor JF, Thurm H, et al. Brain penetration of Lorlatinib: cumulative Incidences of CNS and non-CNS progression with Lorlatinib in patients with previously treated ALK-positive non-small-cell lung cancer. Target Oncol. 2020;15(1):55–65. doi: 10.1007/s11523-020-00702-4. - DOI - PMC - PubMed
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