Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb;23(1):39-64.
doi: 10.1007/s40368-021-00635-0. Epub 2021 Jun 10.

An update of treatment modalities in children and adolescents with teeth affected by molar incisor hypomineralisation (MIH): a systematic review

C Somani  1 , G D Taylor  2 , E Garot  3 , P Rouas  3 , N A Lygidakis  4 , F S L Wong  5
Affiliations

An update of treatment modalities in children and adolescents with teeth affected by molar incisor hypomineralisation (MIH): a systematic review

C Somani et al. Eur Arch Paediatr Dent. 2022 Feb.

Abstract

Purpose: To systematically review the treatment modalities for molar-incisor hypomineralisation for children under the age of 18 years. The research question was, 'What are the treatment options for teeth in children affected by molar incisor hypomineralisation?'

Methods: An electronic search of the following electronic databases was completed MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, LILACS, Google Scholar and Open Grey identifying studies from 1980 to 2020. The PRISMA guidelines were followed. The studies were screened, data extracted and calibration was completed by two independent reviewers.

Results: Of 6220 potential articles, 34 studies were included. Twenty studies investigated management of molars with fissure sealants, glass ionomer cement, polyacid modified resin composite, composite resin, amalgam, preformed metal crowns, laboratory-manufactured crowns and extractions. In four articles management of incisors with microabrasion, resin-infiltration and a combination of approaches was reported. Eight studies looked at strategies to mineralise MIH-affected teeth and/or reduce hypersensitivity. Two studies investigated patient-centred outcomes following treatment. Due to the heterogeneity between the studies, meta-analysis was not performed.

Conclusion: The use of resin-based fissure sealants, preformed metal crowns, direct composite resin restorations and laboratory-made restorations can be recommended for MIH-affected molars. There is insufficient evidence to support specific approaches for the management of affected incisors. Products containing CPP-ACP may be beneficial for MIH-affected teeth.

Keywords: Children; Developmental dental defect; Management; Molar incisor hypomineralisation.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
PRISMA flow diagram
Fig. 2
Fig. 2
Rias of bias assessment for randomised trials
Fig. 3
Fig. 3
Rias of bias assessment for non-randomised trials
Fig. 3
Fig. 3
Rias of bias assessment for non-randomised trials
Fig. 3
Fig. 3
Rias of bias assessment for non-randomised trials
See this image and copyright information in PMC

References

    1. Ahovuo-Saloranta A, Forss H, Hiiri A, Nordblad A, Mäkelä M. Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database Syst Rev. 2016 doi: 10.1002/14651858.CD003067.pub4. - DOI - PMC - PubMed
    1. Alkhalaf R, de Neves A, A, Banerjee A, Hosey MT. Minimally invasive judgement calls: managing compromised first permanent molars in children. Br Dent J. 2020;229(7):459–465. doi: 10.1038/s41415-020-2154-x. - DOI - PubMed
    1. Ashley P, Noar J. Interceptive extractions for first permanent molars: a clinical protocol. Br Dent J. 2019;227(3):192–195. doi: 10.1038/s41415-019-0561-7. - DOI - PubMed
    1. Bakkal M, Abbasoglu Z, Kargul B. The effect of casein phosphopeptide-amorphous calcium phosphate on molar-incisor hypomineralisation: a pilot study. Oral Health Prev Dent. 2017;15(2):163–167. - PubMed
    1. Banerjee A. “Minimum intervention”—MI inspiring future oral healthcare? Br Dent J. 2017;223(3):133–135. doi: 10.1038/sj.bdj.2017.644. - DOI - PubMed

Publication types

LinkOut - more resources