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. 2021 Jun 9;29(6):849-851.
doi: 10.1016/j.chom.2021.05.003.

Unleashing natural antibodies against HIV-1

Noam Ben-Shalom  1 , Natalia T Freund  2
Affiliations
Free article

Unleashing natural antibodies against HIV-1

Noam Ben-Shalom et al. Cell Host Microbe. .
Free article

Abstract

One barrier to HIV-1 eradication is the viral Env protein that is invisible to most antibodies. In this issue of Cell Host & Microbe, Rajashekar et al. (2021) remove the "invisibility cloak" from Env, make it accessible to antibodies, and demonstrate NK-mediated in vivo killing of infected cells by human plasma antibodies.

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