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Comment
. 2021 Oct;23(10):2009-2010.
doi: 10.1038/s41436-021-01235-5. Epub 2021 Jun 10.

Correspondence on "Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation" by Thompson et al

Carmen Suay-Corredera  1 , Jorge Alegre-Cebollada  2
Affiliations
Comment

Correspondence on "Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation" by Thompson et al

Carmen Suay-Corredera et al. Genet Med. 2021 Oct.
No abstract available

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Comment in

  • Response to Suay-Corredera et al.
    Thompson AD, Day SM. Thompson AD, et al. Genet Med. 2021 Oct;23(10):2011-2012. doi: 10.1038/s41436-021-01236-4. Epub 2021 Jun 16. Genet Med. 2021. PMID: 34135487 No abstract available.

Comment on

References

    1. Marian Ali, J. & Braunwald, E. Hypertrophic cardiomyopathy. Circ. Res. 121, 749–770 (2017). - DOI
    1. Semsarian, C. & Ingles, J. in Hypertrophic Cardiomyopathy (ed Naidu, S. S). Genetics of HCM and role of genetic testing. (Springer-Verlag, London, 2015).
    1. Thompson, A. D. et al. Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation. Genet. Med. https://doi.org/10.1038/s41436-021-01134-9 (2021).
    1. Ababou, A. et al. Myosin binding protein C positioned to play a key role in regulation of muscle contraction: structure and interactions of domain C1. J. Mol. Biol. 384, 615–630 (2008). - DOI
    1. Smelter, D. F., Lange, W. J. D., Cai, W., Ge, Y. & Ralphe, J. C. The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability. Am J Physioll Heart Circ Physiol 314, H1179–H1191 (2018). - DOI

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