Immunothrombosis: a COVID-19 concerto

George Goshua^{1

2}, Ayesha Butt¹, Alfred I Lee¹

Affiliations

¹ Section of Hematology, Yale School of Medicine, New Haven, CT, USA.
² Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Comment

George Goshua et al. Br J Haematol. 2021 Aug.

. 2021 Aug;194(3):491-493.

doi: 10.1111/bjh.17666. Epub 2021 Jul 7.

George Goshua^{1

2}, Ayesha Butt¹, Alfred I Lee¹

¹ Section of Hematology, Yale School of Medicine, New Haven, CT, USA.
² Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

No abstract available

Comment on

COVID-19 and immunothrombosis: emerging understanding and clinical management.
Shaw RJ, Bradbury C, Abrams ST, Wang G, Toh CH. Shaw RJ, et al. Br J Haematol. 2021 Aug;194(3):518-529. doi: 10.1111/bjh.17664. Epub 2021 Jul 7. Br J Haematol. 2021. PMID: 34114204 Review.

1. Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, et al. Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19. N Engl J Med. 2020;383:120-8.
1. Hottz ED, Azevedo-Quintanilha IG, Palhinha L, Teixeira L, Barreto EA, Pão CR, et al. Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19. Blood. 2020;136:1330-41.
1. Middleton E, Cody M, Rondina M. Neutrophil extracellular traps (NETs) contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome clinical trial registration information (if any). Blood. 2020;136:1169-79.
1. Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, et al. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. Lancet Haematol. 2020;7:e575-e582.
1. Magro C, Mulvey JJ, Berlin D, Nuovo G, Salvatore S, Harp J, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res. 2020;220:1-13.