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. 2021 Aug;8(8):717-731.
doi: 10.1016/S2215-0366(21)00009-2. Epub 2021 Jun 8.

The epidemiology of psychiatric disorders in Africa: a scoping review

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The epidemiology of psychiatric disorders in Africa: a scoping review

M Claire Greene et al. Lancet Psychiatry. 2021 Aug.

Abstract

This scoping review of population-based epidemiological studies was done to provide background information on the prevalences and distribution of psychiatric disorders in Africa for calls to broaden diversity in psychiatric genetic studies. We searched PubMed, EMBASE, and Web of Science to retrieve relevant literature in English, French, and Portuguese from Jan 1, 1984, to Aug 18, 2020. In 36 studies from 12 African countries, the lifetime prevalence ranged from 3·3% to 9·8% for mood disorders, from 5·7% to 15·8% for anxiety disorders, from 3·7% to 13·3% for substance use disorders, and from 1·0% to 4·4% for psychotic disorders. Although the prevalence of mood and anxiety disorders appears to be lower than that observed in research outside the continent, we identified similar distributions by gender, although not by age or urbanicity. This review reveals gaps in epidemiological research on psychiatric disorders and opportunities to leverage existing epidemiological and genetic research within Africa to advance our understanding of psychiatric disorders. Studies that are methodologically comparable but diverse in geographical context are needed to advance psychiatric epidemiology and provide a foundation for understanding environmental risk in genetic studies of diverse populations globally.

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Conflict of interest statement

Declaration of interests PFS reports personal fees and other from RBNC Therapeutics, outside the submitted work. AMcl reports personal fees from Janssen, personal fees from Illumina, grants from The Sackler Trust, outside the submitted work. JW reports grants from Takeda Pharmaceuticals, outside the submitted work. MMW reports research grants in the past 3 years from National Institute for Mental Health, Brain and Behavior Research Foundation, Templeton Foundation, and has received book royalties from the Perseus Press, Oxford Press, and APA Publishing. MMW has also received royalties on the social adjustment scale from Multihealth Systems. All other authors declare no competing interests. The Lancet Group takes a neutral position with respect to territorial claims in published tables, figures, and institutional affiliations.

Figures

Figure 1:
Figure 1:. Screening and selection of articles
Figure 2:
Figure 2:. Range of prevalence estimates by disorder as compared with the World Mental Health Survey estimates
Range of point, period, and lifetime prevalence estimates for studies done in Africa. The shapes display lifetime prevalence estimates from selected countries included in the World Mental Health Survey initiative.

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