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Comment
. 2021 Aug;100(2):471-472.
doi: 10.1016/j.kint.2021.06.006. Epub 2021 Jun 10.

Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination

Affiliations
Comment

Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination

Allan Sacker et al. Kidney Int. 2021 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Antiglomerular basement membrane (GBM) antibody disease nephritis after severe acute respiratory syndrome coronavirus 2 vaccination. (a) Diffusely crescentic glomerulonephritis, with necrosis, cellular crescents, and destruction of the glomerular tuft and Bowman’s capsule (Jones stain, original magnification ×200). (b) Linear staining of GBMs for IgG (original magnification ×200). (c) Mesangial deposition of IgA by immunofluorescence (original magnification ×400). (d) Rare mesangial deposits by electron microscopy. Direct magnification ×6800. Bar = 800 nm. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org.

Comment on

  • Is COVID-19 vaccination unmasking glomerulonephritis?
    Tan HZ, Tan RY, Choo JCJ, Lim CC, Tan CS, Loh AHL, Tien CS, Tan PH, Woo KT. Tan HZ, et al. Kidney Int. 2021 Aug;100(2):469-471. doi: 10.1016/j.kint.2021.05.009. Epub 2021 May 23. Kidney Int. 2021. PMID: 34033857 Free PMC article. No abstract available.

References

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    1. Canney M., O'Hara P.V., McEvoy C.M. Spatial and temporal clustering of anti-glomerular basement membrane disease. Clin J Am Soc Nephrol. 2016;11:1392–1399. - PMC - PubMed
    1. Prendecki M., Clarke C., Cairns T. Anti–glomerular basement membrane disease during the COVID-19 pandemic. Kidney Int. 2020;98:780–781. - PMC - PubMed