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Review
. 2021 Nov;41(11):2041-2044.
doi: 10.1007/s00296-021-04915-2. Epub 2021 Jun 13.

Pulmonary nodular lymphoid hyperplasia and Sjögren's syndrome: a case report and literature review

Aina Darder  1 , Ines Losada Lopez  2   3 , Cristina Gomez-Bellvert  4 , Adrian Rodriguez  2   3 , Eugenia Cisneros  2   3 , Juan Gonzalez-Moreno  5   6
Affiliations
Review

Pulmonary nodular lymphoid hyperplasia and Sjögren's syndrome: a case report and literature review

Aina Darder et al. Rheumatol Int. 2021 Nov.

Abstract

Pulmonary nodular lymphoid hyperplasia, also known as pseudolymphoma, is an uncommon reactive lymphoproliferative disorder of unknown etiology that can be found in Sjögren's syndrome patients. Here, we present a case of a previously healthy woman in which the incidental finding of a lung mass compatible with nodular lymphoid hyperplasia led to the subsequent diagnosis of Sjögren's syndrome. We also performed a literature review for the association between both entities and described the main clinical aspects of the reported cases. Although its rarity, we consider that pulmonary nodular lymphoid hyperplasia should be considered in the differential diagnosis of lung nodules or masses among Sjögren's syndrome patients.

Keywords: Lymphocytoma; Pseudolymphoma; Reactive lymphoid hyperplasia; Sjögren’s syndrome.

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