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Review
. 2021 Aug;21(8):e2100160.
doi: 10.1002/mabi.202100160. Epub 2021 Jun 13.

Supercritical Fluid-Based Decellularization Technologies for Regenerative Medicine Applications

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Review

Supercritical Fluid-Based Decellularization Technologies for Regenerative Medicine Applications

Beom-Seok Kim et al. Macromol Biosci. 2021 Aug.

Abstract

Supercritical fluid-based extraction technologies are currently being increasingly utilized in high purity extract products for food industries. In recent years, supercritical fluid-based extraction technology is transformed in biomaterials process fields to be further utilized for tissue engineering and other biomedical applications. In particular, supercritical fluid-based decellularization protocols have great advantage over the conventional decellularization as it may allow preservation of extracellular matrix components and structures. In this review, the latest technological development utilizing the supercritical fluid-based decellularization for regenerative medicine is introduced.

Keywords: biomaterial; decellularization; regenerative medicine; supercritical fluid; tissue engineering.

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