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. 2021 Jun;28(6):3523-3525.
doi: 10.1016/j.sjbs.2021.03.022. Epub 2021 Mar 18.

Relationship between high CRP and cytokines in Saudi old people with dental caries in alkharj Region, Saudi Arabia

Arwa F Alanazi  1 , Awwad Alenezy  2 , Amna Alotiby  3 , Talat Bukhari  3 , Wael Alturaiki  4 , Abdulkarim S BinShaya  5 , Hisham Ali Waggiallah  5 , Harbi W  5 , Kahtani Y  5 , Majli K  5 , Amani F Alanazi  6 , Faris Q B Alenzi  5
Affiliations

Relationship between high CRP and cytokines in Saudi old people with dental caries in alkharj Region, Saudi Arabia

Arwa F Alanazi et al. Saudi J Biol Sci. 2021 Jun.

Abstract

Objective: Dental caries is one of the most common problems of the oral cavity which is frequently observed in older people. The aim of this study is to evaluate serum C-reactive proteins (CRP) levels and to identify the correlation between dental caries and CRP levels.

Methodology: The study included 12 aged patients with an average age of 65-years; the patients were diagnosed with dental caries and did not have clinical history of heart diseases, rheumatoid arthritis or any other infection. The control group consisted of 10 healthy donors with an average age of 60-years. The CRP level of positive samples was measured by using CRP Enzyme-linked immunosorbent assay-ELISA Kit.

Results: The currents study showed that only 5 out of 12 patients were CRP positive.

Conclusions: Because of study limitations, it is early to conclude of close relationship between serum CRP and dental caries from the findings of this study; however, this study will give a clearer picture to understand the relationship between serum CRP, inflammatory cytokines and dental caries.

Keywords: Bacterial infection; CRP; Cytokines; Oral cavity; Tooth loss.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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