Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Aug:35:102056.
doi: 10.1016/j.bcab.2021.102056. Epub 2021 Jun 7.

Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review

P Prakash  1 , R Meena  2 , L Stanley Abraham  3 , Swetha Sunkar  4 , K Govindaraju  3 , Durgasruthi Pully  5 , Antony V Samrot  6
Affiliations
Review

Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review

P Prakash et al. Biocatal Agric Biotechnol. 2021 Aug.

Abstract

The recent outbreak of COVID-19 is attributed to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This viral disease is rapidly spreading across the globe, including India. The mainstay in managing the disease is supportive care, nutrition, and preventing further progression in the absence of proven antiviral drugs. Currently two vaccines Covishield and Covaxin are administered in India. Long-term plans of developing most reliable mRNA-based vaccines are also underway for the future method of prophylaxis. The Siddha system of medicine's holistic approach emphasizes lifestyle modification, prophylactic interventions, and dietary management to boost the host immunity and treatment with herbal medicines and higher-order medicines as the case may be. In this review, a brief outline of the disease COVID-19, Coronavirus, evidence-based traditional Siddha interventions for respiratory ailments and immune boosters highlighting the relevant published research on individual herbs are dealt, which pave way for further research on drug repurposing for COVID-19. Historical evidence on the prevention and treatment of infections especially antivirals in Siddha classics is studied.

Keywords: Antiviral property; COVID - 19; Immunomodulatory drugs; Pandemic; SARS-CoV-2; Siddha.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Structure of coronavirus (COVID-19).
Fig. 2
Fig. 2
SARS-CoV-2 Pathogenesis and different potent Drug targets.
See this image and copyright information in PMC

References

    1. Al-Ansari Mysoon M., Singh A.J.A.Ranjit, Al-Khattaf Fatimah S., Michael J.S. Nano-formulation of herbo-mineral alternative medicine from linga chenduram and evaluation of antiviral efficacy. Saudi J. Biol. Sci. 2021;28(3):1596–1606. - PMC - PubMed
    1. Ali B.H., Blunden G., Tanira M.O., Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem. Toxicol. 2008;46:409–420. doi: 10.1016/j.fct.2007.09.085. - DOI - PubMed
    1. Anaivarai R. In: A Compendium of Siddha Doctrine. first ed. Anandhan, editor. Department of Indian Medicine and Homoeopathy; Chennai: 2005.
    1. Anaivarai R. In: Principles of Diagnosis in Siddha-Part 1. first ed. Anandhan, editor. Department of Indian Medicine and Homoeopathy; Chennai: 2009.
    1. Anbarasu K., Manisenthil K.K., Ramachandran S. Antipyretic, anti-inflammatory and analgesic properties of Nilavembu kudineer choornam: a classical preparation used in the treatment of chikungunya fever. Asian Pac J Trop Med. 2011;4:819–823. doi: 10.1016/S1995-7645(11)60201-0. - DOI - PubMed

LinkOut - more resources