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. 2021 Jun 14;39(6):725-729.
doi: 10.1016/j.ccell.2021.05.016.

Innate immune cells in the tumor microenvironment

Ming O Li, Natalie Wolf, David H Raulet, Leila Akkari, Mikael J Pittet, Paulo C Rodriguez, Rosandra N Kaplan, Ariel Munitz, Zemin Zhang, Sijin Cheng, Nina Bhardwaj
Free article

Innate immune cells in the tumor microenvironment

Ming O Li et al. Cancer Cell. .
Free article

Abstract

The tumor immune microenvironment (TIME) is a complex ecosystem that contains adaptive and innate immune cells that have tumor-promoting and anti-tumor effects. There is still much to learn about the diversity, plasticity, and functions of innate immune cells in the TIME and their roles in determining the response to immunotherapies. Experts discuss recent advances in our understanding of their biology in cancer as well as outstanding questions and potential therapeutic avenues.

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