The Kringle of Life

Manuel Llinás^{1

2}

Affiliations

¹ Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, 16802, USA. manuel@psu.edu.
² Department of Chemistry, Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA, 16802, USA. manuel@psu.edu.

Manuel Llinás. Protein J. 2021 Aug.

. 2021 Aug;40(4):454-456.

doi: 10.1007/s10930-021-10009-6. Epub 2021 Jun 16.

Manuel Llinás^{1

2}

¹ Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, 16802, USA. manuel@psu.edu.
² Department of Chemistry, Huck Center for Malaria Research, The Pennsylvania State University, University Park, PA, 16802, USA. manuel@psu.edu.

No abstract available

References

1. Allman EL, Painter HJ, Samra J, Carrasquilla M, Llinás M. “Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways.” Antimicrobial Agents and Chemotherapy. 2016; pii: AAC.01224–16.
1. Byeon IJ, Kelley RF, Llinás M (1989) 1H NMR structural characterization of a recombinant kringle 2 domain from human tissue-type plasminogen activator. Biochemistry 28(24):9350–9360. https://doi.org/10.1021/bi00450a016 - DOI - PubMed - PMC
1. Cellitti J, Llinás M, Echols N, Shank EA, Gillespie B, Kwon E, Crowder SM, Dahlquist FW, Alber T, Marqusee S (2007) Exploring subdomain cooperativity in T4 lysozyme I: structural and energetic studies of a circular permutant and protein fragment. Protein Sci 16(5):842–851 - DOI
1. Christen MT, Frank P, Schaller J, Llinás M (2010) Human plasminogen kringle 3: solution structure, functional insights, phylogenetic landscape. Biochemistry 49(33):7131–7150. https://doi.org/10.1021/bi100687f - DOI - PubMed - PMC
1. Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M (2013) kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in plasmodium falciparum. J Biol Chem 288(51):36338–36350 - DOI