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Case Reports
. 2021 Sep;64(3):E13-E15.
doi: 10.1002/mus.27351. Epub 2021 Jun 23.

COVID-19-accelerated disease progression in two patients with amyotrophic lateral sclerosis

Xiaoyan Li  1 , Richard Bedlack  1
Affiliations
Case Reports

COVID-19-accelerated disease progression in two patients with amyotrophic lateral sclerosis

Xiaoyan Li et al. Muscle Nerve. 2021 Sep.
No abstract available

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Conflict of interest statement

R.B. has received research support from ALS Association, MediciNova, and Orion, and served as a paid consultant for Alexion, ALS Association, Amylyx, Biogen, Brainstorm Cell, Mallinkrodt, MT Pharma, New Biotic, Orphazyme, and Woolsey Pharma. X.L. declares no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Rapid decline of revised ALSFRS‐R in two amyotrophic lateral sclerosis patients post–COVID‐19 infection. A, Slow decline of ALSFRS‐R in patient 1, which plateaued from January 2019 to September 2020, but declined rapidly after COVID‐19 infection. B, Stable ALSFRS‐R between 2013 and 2019 in patient 2, followed by a rapid decline in 2020 after COVID‐19 infection. ↓ indicates postinfection ALSFRS‐R. Abbreviation: ALSFRS‐R, revised Amyotropic Lateral Sclerosis Functional Rating Scale
See this image and copyright information in PMC

References

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