Conceptual simplicity in pursuit of precision

Affiliations

¹ Pulmonary and Critical Care Medicine, University of Minnesota and Regions Hospital, Minneapolis, MS 11203B, 640 Jackson St., Saint Paul, MN, 55101, USA. marin002@umn.edu.
² Department of Mathematics, Vanderbilt University, Nashville, TN, USA.
³ Department of Anesthesiology, Intensive Care and Emergency Medicine, Medical University of Göttingen, Göttingen, Germany.

Comment

John J Marini et al. Intensive Care Med. 2021 Aug.

. 2021 Aug;47(8):920-921.

doi: 10.1007/s00134-021-06424-z. Epub 2021 Jun 16.

¹ Pulmonary and Critical Care Medicine, University of Minnesota and Regions Hospital, Minneapolis, MS 11203B, 640 Jackson St., Saint Paul, MN, 55101, USA. marin002@umn.edu.
² Department of Mathematics, Vanderbilt University, Nashville, TN, USA.
³ Department of Anesthesiology, Intensive Care and Emergency Medicine, Medical University of Göttingen, Göttingen, Germany.

No abstract available

Comment on

Intra-cycle power: is the flow profile a neglected component of lung protection?
Marini JJ, Crooke PS, Gattinoni L. Marini JJ, et al. Intensive Care Med. 2021 May;47(5):609-611. doi: 10.1007/s00134-021-06375-5. Epub 2021 Apr 2. Intensive Care Med. 2021. PMID: 33797574 Free PMC article. No abstract available.
Is airway regional resistances array a neglected component of ventilation?
Hicter JF, Drevon J, Vallier S. Hicter JF, et al. Intensive Care Med. 2021 Aug;47(8):918-919. doi: 10.1007/s00134-021-06429-8. Epub 2021 May 18. Intensive Care Med. 2021. PMID: 34003329 Free PMC article. No abstract available.

1. Hicter J-F, Drevon J, Vallier S (2021) Is airway regional resistances array a neglected component of ventilation? Intensive Care Med. https://doi.org/10.1007/s00134-021-06429-8
1. Marini JJ, Crooke PS, Gattinoni L (2021) Intra-cycle power: is the flow profile a neglected component of lung protection? Intensive Care Med. https://doi.org/10.1007/s00134-021-06375-5
1. Hotchkiss JR, Crooke PS, Adams AB, Marini JJ (1993) Implications of a biphasic two-compartment model of constant flow ventilation for the clinical setting. J Crit Care 9(2):114–123 - DOI
1. Crooke PS, Kaynar AM, Hotchkiss JR (2010) A mathematical model of airflow induced regional over-distention during mechanical ventilation: Comparing pressure-controlled and volume-controlled modes. Lecture Notes Control Inf Sci 407:269–281. https://doi.org/10.1007/978-3-642-16135-3 - DOI
1. Wlison TA (1998) Parenchymal macromechanics. In: Hlastala MP, Robertson HT (eds) Chapter 3 in complexity in structure and function of the lung. Marcel Dekker, New York, pp 75–98