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Editorial
. 2021 Sep 1;23(9):1423-1424.
doi: 10.1093/neuonc/noab146.

Serum cell-free DNA epigenetic biomarkers aid glioma diagnostics and monitoring

Kevin C Johnson  1 , Roel G W Verhaak  1   2
Affiliations
Editorial

Serum cell-free DNA epigenetic biomarkers aid glioma diagnostics and monitoring

Kevin C Johnson et al. Neuro Oncol. .
No abstract available

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Comment on

  • A serum-based DNA methylation assay provides accurate detection of glioma.
    Sabedot TS, Malta TM, Snyder J, Nelson K, Wells M, deCarvalho AC, Mukherjee A, Chitale DA, Mosella MS, Sokolov A, Asmaro KP, Robin A, Rosenblum ML, Mikkelsen T, Rock J, Poisson LM, Lee I, Walbert T, Kalkanis S, Iavarone A, Castro AV, Noushmehr H. Sabedot TS, et al. Neuro Oncol. 2021 Sep 1;23(9):1494-1508. doi: 10.1093/neuonc/noab023. Neuro Oncol. 2021. PMID: 33560371 Free PMC article.

References

    1. Martinez-Ricarte F, Mayor R, Martínez-Sáez E, et al. . Molecular diagnosis of diffuse gliomas through sequencing of cell-free circulating tumor DNA from cerebrospinal fluid. Clin Cancer Res. 2018;24;2812–2819. - PubMed
    1. Müller Bark J, Kulasinghe A, Chua B, Day BW, Punyadeera C. Circulating biomarkers in patients with glioblastoma. Br J Cancer. 2020;122(3):295–305. - PMC - PubMed
    1. Shi W, Lv C.Qi J, et al. . Prognostic value of free DNA quantification in serum and cerebrospinal fluid in glioma patients. J Mol Neurosci. 2012;46:470–475. - PubMed
    1. Miller AM, Shah RH, Pentsova EI, et al. . Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid. Nature. 2019;565:654–658. - PMC - PubMed
    1. Mouliere F, Mair R, Chandrananda D, et al. . Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients. EMBO Mol Med. 2018;10(12):e9323. - PMC - PubMed