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Case Reports
. 2021 May 30:38:101734.
doi: 10.1016/j.eucr.2021.101734. eCollection 2021 Sep.

Giant primary vaginal tubulovillous adenoma: A case report and review of literature

Michael L Creswell  1 , Charmaine Jl Ilagan  2 , Sarah G Downs  3 , Louis A Dainty  3 , Keith Kowalczyk  4 , Nathan M Shaw  4
Affiliations
Case Reports

Giant primary vaginal tubulovillous adenoma: A case report and review of literature

Michael L Creswell et al. Urol Case Rep. .

Abstract

Primary adenomas are common in the gastrointestinal tract but exceedingly rare on the periurethral surface and vagina. The pathogenesis remains unknown but vaginal adenomas are hypothesized to arise from vaginal adenosis or embryonic cloacal remnants and possess malignant potential. We present a case of a large primary vaginal tubulovillous adenoma in an eighty-one-year-old, likely diethylstilbestrol naïve patient. To the best of our knowledge the patient's 7.4 x 4.5 × 1.4 cm primary vaginal tubulovillous adenoma is the largest ever reported in literature.

Keywords: Enteric tumor; Tubulovillous adenoma; Urethral mass; Vaginal mass.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Axial computed tomography (CT) of the pelvis. Image demonstrates a ~5x3cm soft tissue defect in the vaginal region.
Fig. 2
Fig. 2
Intra-operative photograph of large mucinous-appearing mass.
Fig. 3
Fig. 3
The tubulovillous adenoma appears to have developed from squamous mucosa. On microscopy there a clear transition from squamous mucosa developing to a tubulovillous adenoma. (Hematoxylin and eosin; x100).
See this image and copyright information in PMC

References

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