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Case Reports
. 2021 Jan 22;59(7):e285-e287.
doi: 10.1515/cclm-2020-1704. Print 2021 Jun 25.

A case of methaemoglobinaemia interference on the WDF channel on Sysmex XN-Series analysers

Jérôme Debus  1 , Bénédicte Dumont  1 , Blaise Naomi Kouadio  1 , Noémie Zucman  2   3 , Louis-Marie Dumont  2 , Edith Peynaud-Debayle  1
Affiliations
Case Reports

A case of methaemoglobinaemia interference on the WDF channel on Sysmex XN-Series analysers

Jérôme Debus et al. Clin Chem Lab Med. .
No abstract available

Keywords: Sysmex analyser; interference; methaemoglobin; scattergram; white blood cell differential.

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References

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    1. McCabe, A, McCann, B, Kelly, P. Pop goes the O2: a case of popper-induced methaemoglobinamia. BMJ Case Rep 2012;2012:bcr2012007176. https://doi.org/10.1136/bcr-2012-007176.
    1. Teixeira, C, Pina, D, Freitas, MI. Automated detection of unstable hemoglobin variants by Sysmex XE-Series analyzers. Clin Chem Lab Med 2017;55:e243–6. https://doi.org/10.1515/cclm-2017-0231.
    1. Rosetti, M, Poletti, G, Sensi, A, Ravani, A, Rondoni, M, Baldrati, L, et al.. A rare case of Hemoglobin Leiden interfering with the DIFF channel of Sysmex XE-2100. Scand J Clin Lab Invest 2015;75:43–7. https://doi.org/10.3109/00365513.2015.1033743.
    1. Mongelli, F, Barberio, G, Ivaldi, G. A rare and unstable hemoglobin variant, Hb M Dothan β 25/26 (-GTG), detected by the anomalous cytogram on Sysmex XE-2100. Clin Chem Lab Med 2016;54:e31–3. https://doi.org/10.1515/cclm-2015-0566.

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