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Case Reports
. 2021 Aug;100(2):468-469.
doi: 10.1016/j.kint.2021.06.011. Epub 2021 Jun 17.

Histologic correlates of gross hematuria following Moderna COVID-19 vaccine in patients with IgA nephropathy

Satoru Kudose  1 , Paul Friedmann  2 , Oltjon Albajrami  3 , Vivette D D'Agati  4
Affiliations
Case Reports

Histologic correlates of gross hematuria following Moderna COVID-19 vaccine in patients with IgA nephropathy

Satoru Kudose et al. Kidney Int. 2021 Aug.
No abstract available

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Figures

Figure 1
Figure 1
(a) Light microscopy from patient 1 shows a glomerulus with fibrinoid necrosis associated with rupture of the glomerular basement membranes (arrows), and a small cellular crescent (periodic acid–Schiff). Original magnification ×1000. (b) Immunofluorescence demonstrates 3+ granular global mesangial staining for IgA. Original magnification ×600. (c) Light microscopy from patient 2 shows a glomerulus with segmental endocapillary hypercellularity including infiltrating neutrophils on a background of mesangial hypercellularity (periodic acid–Schiff). Original magnification ×600. (d) A glomerulus with a segmental scar contains an overlying segmental fibrous crescent with rupture of Bowman’s capsule (periodic acid–Schiff). Original magnification ×600. (a–d) Bars = 50 μm. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org.
See this image and copyright information in PMC

References

    1. Negrea L., Rovin B.H. Gross hematuria following vaccination for severe acute respiratory syndrome coronavirus 2 in 2 patients with IgA nephropathy. Kidney Int. 2021;99:1487. - PMC - PubMed
    1. Rahim S.E.G., Lin J.T., Wang J.C. A case of gross hematuria and IgA nephropathy flare-up following SARS-CoV-2 vaccination. Kidney Int. 2021;100:238. - PMC - PubMed
    1. Tan H.Z., Tan R.Y., Choo J.C.J. Is COVID-19 vaccination unmasking glomerulonephritis? Kidney Int. 2021;100:469–471. - PMC - PubMed
    1. Kudose S., Batal I., Santoriello D. Kidney biopsy findings in patients with COVID-19. J Am Soc Nephrol. 2020;31:1959–1968. - PMC - PubMed

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